Krystal Biotech announced the first patient has been dosed in EMERALD-1, its phase 1/2 clinical trial evaluating KB801 for ...

by epithelial cells in the front of the eye for the treatment of neurotrophic keratitis (NK), a rare, degenerative corneal disease that leads to corneal epithelial defects, ulcers, and perforation.

About KB801 KB801 is a redosable eye drop gene therapy designed to enable sustained, localized expression and secretion of nerve growth factor (NGF) by epithelial cells in the front of the eye for the ...

KB801 is a redosable eye drop gene therapy in development for the treatment of NK, a degenerative corneal disease characterized by damage or loss of function in the neurons innervating the eye ...

Krystal Biotech climbs after dosing begins in a phase I/II trial for KB801, a gene therapy eye drop targeting neurotrophic keratitis.

A 64-year-old woman presented to an outside provider with 5 days of left eye “burning, itching, redness and blurry vision” ...

Additional exploratory efficacy measures will include change in corneal lesion size from baseline, each assessed at weeks 4, 6, 8, 10, and 20, as well as evaluations of corneal sensation and ...

PITTSBURGH, July 09, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS) announced today that the first patient has been dosed in its Phase 1/2 clinical trial (“EMERALD-1”), ...

Conjunctivitis: Inflammation of the conjunctiva, leading to red, watery eyes. Corneal Ulcers: Damaged cornea that may result from trauma or infection. Cataracts: Clouding of the eye's lens ...

Ulcers: Corneal damage, removing the surface layers of the cornea. Ulcers tend to be painful, so they are often associated with other signs, like squinting and redness.

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