The mechanisms governing natural killer cell development are not well understood. Activation of the tyrosine kinase receptors Tyro3, Axl and Mer on pre–natural killer cells by stromal cell ...

The mechanism used by "natural killer" immune cells in the human body to distinguish between diseased cells, which they are meant to destroy, and normal cells, which they are meant to leave alone ...

Researchers reveal key mechanism of NK cell dysfunction. University of Science and Technology of China. Journal Nature Immunology DOI 10.1038/s41590-023-01462-9. Keywords ...

Receptor engineering has significantly advanced NK cell-based cancer immunotherapies. As technical hurdles are overcome, ...

Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies Date: May 3, 2024 Source: German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Francisco de Souza, Hugo. (2024, February 22). Natural killer cells lead the charge in cancer ...

Emerging intracellular checkpoint molecules offer new targets for improving NK cell antitumor activity, and understanding their mechanisms of action is crucial for identifying targetable checkpoints.

(PhysOrg.com) -- The mechanism used by 'Natural Killer' immune cells in the human body to distinguish between diseased cells, which they are meant to destroy, and normal cells, which they are ...

Interventions in this mechanism could potentially improve the efficacy of these ... The immunoglobulin superfamiliy ligand B7H6 subjects T cell responses to NK cell surveillance. Science ...

Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies. ... Platten's team identified the protein B7H6 as a recognition molecule for NK cell attacks in a new study.