A three-component construction of eight-membered nitrogen-containing heterocycles via palladium-catalyzed imidoylative cyclization of 2-isocyano-N-(propa-1,2-dien-1-yl)benzamides with aryl halides and ...

Pyridones are versatile building blocks in organic synthesis and a privileged motif in drug discovery. However, N-substituted 2-pyridones bearing an α-tertiary carbon, cyclopropyl, or heterocycle off ...

Karen Conti: Reasoning behind letter from jury to judge in Sean ‘Diddy’ Combs trial by: Hayley Boyd Posted: Jul 2, 2025 / 11:13 AM CDT Updated: Jul 2, 2025 / 11:13 AM CDT Karen Conti, Chicago trial ...

NH Politics Christian Urrutia launches N.H. Democratic campaign for Congressional District 1 The former Biden appointee is among at least five candidates seeking the seat that Representative Chris ...

The president cited a hypothetical letter to Japanese leaders — but with one major flaw.

IDEAS A book that changed my mind: ‘The Screwtape Letters’ I’m a secular humanist who used to sneer at religion. Now I stand up for it.