This study explores the use of polarized second-harmonic generation (pSHG) to investigate myosin conformation in the relaxed state, differentiating between the actin-available, disordered (ON) state ...

While their functions are diverse, myosins are similar in structure. NMII is so much like cardiac myosin, which keeps the ...

Myosin Therapeutics, a clinical-stage biotechnology company advancing first-in-class therapies targeting molecular motor proteins, announced the publication of two major papers in the journal Cell ...

The chirality of tissues and organs is essential for their proper function and development. Tissue-level chirality derives from the chirality of individual cells that comprise the tissue, and cellular ...

With intensifying global warming and climate change, drought has become a major threat to global agriculture, impacting crop ...

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects motor neurons, leading to ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...