Our cells move energy and matter to the places it is needed. But how do they do this in real time, and seen from the perspective of a single molecule? Scientists have successfully uncovered new ...

The proteins MmpL5 and MmpL4 are efflux transporters, critical pumps that help the pathogen M. tuberculosis grow by scavenging essential iron from the iron-deprived lung granulomas of its human host.

The first specific correlations between cell membrane transporters or pumps and a drug-resistant phenotype were made in Chinese hamster ovary cell lines in the mid-1970s, when it was shown that a ...

When further developed, the molecular injectors could shuttle cancer immunotherapies only to tumor cells, sparing healthy ones and limiting side effects. The system can also safely tunnel into the ...

The mission of the Cellular and Molecular Imaging (CMI) Core facility of the Integrative Neuroscience COBRE center is to provide infrastructure and resources necessary to perform cellular and ...

Armed with a deep understanding of the structure of cells, professionals in the field of Cell and Molecular Biology (CMB) are leading the charge against some of the world's most prevalent illnesses ...

University of Queensland researchers have unlocked crucial molecular secrets of aging in cells, potentially paving the way to improve quality of life as people age. The study decoded the process ...

Citation: Stem cells map reveals molecular choreography behind individual variation in human development (2024, September 25) ...

The molecular structure of the MmpL4 efflux pump in Mycobacterium tuberculosis reveals a coiled-coil domain essential for exporting the siderophore mycobactin and for bedaquiline resistance.