Phase 1 results demonstrate that SUL-238, a first-in-class, orally administered, mitochondria-directed drug candidate, is ...

Global population growth presents unprecedented challenges to sustainable food systems, creating an urgent need to innovate nutrient utilization strategies.

At some point during the evolution of life on Earth, inorganic matter became organic, nonliving matter became living. How ...

Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial ...

One bad night of sleep can disrupt your metabolism, but it's easy to get back on track. Here's how to recover from a bad night of sleep, according to doctors.

Is there really a life hack to burn calories in your sleep? A dietitian explains what we know about eating "metabolism-burning foods" before bed.

Fixing problems with cholesterol metabolism might help slow or prevent a common cause of age-related vision loss, a new WashU Medicine study in mice has shown. Pictured are color-stained retinal ...

Metabolic syndrome is common in psoriatic arthritis and is a known risk factor for worse symptoms and poor treatment outcomes. This study sought to explore the syndrome's role in a more precisely ...

A series of diaryl piperidone-sulfonamide derivatives were designed as dual inhibitors of STAT3/CAIX and ferroptosis inducers for triple-negative breast cancer (TNBC). The representative compound 7m ...

In a study recently published in the journal Nature Chemical Biology, researchers reveal that two reactive byproducts of sugar metabolism—methylglyoxal and its metabolite lactoylglutathione ...

In preparing patients for metabolic surgery, a combination of weight loss drugs may be better than GLP-1s or traditional dieting alone Recent findings published in International Journal of Obesity ...