Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial ...

Keywords: fabry disease, enzyme replacement therapy, agalactosidase-α, Markov model, incremental cost-effectiveness ratio, sensitivity analysis Citation: Huang Y, Yuan H and Huang Z (2025) ...

Here, we integrated NMR (Nuclear Magnetic Resonance)-restrained molecular dynamics simulations and a Markov State Model to characterize the free energy landscape and conformational transitions of ...

CRN_Simulation: a package for defining chemical reaction networks (CRNs), simulating the associated continuous-time Markov chain, and solving the chemical master equation by the finite state ...

In this paper, the asynchronous state estimation problem of two-time-scale Markov jump complex networks under analog fading channels is investigated, in which the mode of the designed state estimator ...

Markov state models (MSMs) are a popular model for extracting kinetic information from unbiased molecular dynamics simulations. Recent studies include a wide range of applications, such as ...

This model features one additional parameter over the Michaelis-Menten model, describing the standard deviation of this distribution. HetMM is a program for estimating parameters under the ...