Live recently marked its 50th anniversary with a star-studded celebration, featuring an array of musical guests, including Lil Wayne. The New Orleans rap legend graced the stage alongside The Roots for a rendition of his hit song “Mrs.

Whether it’s shutting down social media critics, clapping back at fellow rappers, or calling out those who fail to give Lil Wayne his due credit, his eldest daughter, Reginae, has always protected her father's legacy.