Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function. Because of this, water molecules represent a powerful but largely ...

Researchers at the University of Illinois Urbana-Champaign have discovered important new clues in the mystery of how an ...

Robust financial performance driven by full year 2024 royalty revenue growth of 28% Reiterating 2025 financial guidance of $180-$200 million in revenues and adjusted earnings per diluted share1 of ...

Overall, the unprecedented molecular-scale study of binding dynamics of a ligand using the steric encumbrance as a design principle on Au (111) brings us one step closer to deciphering real and ...

As a pioneering study, PandoraRLO uses reinforcement learning (RL) to train on a large dataset, through exposure to a wide range of protein-ligand pairs, the agent becomes proficient in comprehending ...

The work could substantially reduce the cost and time associated with developing new drugs. “We developed a theoretical framework for estimating ligand-protein binding,” said Mahmoud Moradi, associate ...

Transcriptional activity is characterized for five steroid receptors complexed with multiple ligands and it is shown that the extent of transcriptional activation in complexes is accurately described ...

One of the most important skills for a biochemist these days is to be able to visualize a protein, find a ligand binding site, and show the three-dimensional interactions with the coordinated amino ...

Within biochemistry, a ligand is defined as any molecule or atom that irreversibly binds to a receiving protein molecule, otherwise known as a receptor.

T. Wohland, K. Friedrich, R. Hovius, H. Vogel, Study of ligand-receptor interactions by fluorescence correlation spectroscopy with different fluorophores: Evidence that the homopentameric ...