Ketamine is a highly effective, fast-acting antidepressant that works even for patients who have not responded to other ...

However, Spravato (esketamine) is a patented nasal spray that contains only the S-ketamine molecule. Spravato has been approved by the FDA for adults with treatment-resistant depression since 2019.

Ketamine has been used since the 1960s as an anesthetic, but in 2000, the first trial of far lower doses of ketamine proved its rapid efficacy in treating major depression and suicidal ideation.

Study models how ketamine's molecular action leads to its effects on the brain. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2024 / 05 / 240521124612.htm.

A new study by Canadian researchers brings us one step closer to understanding the antidepressant effects of ketamine in sub-anesthetic doses. In mice, the researchers identified how two multi ...

In 2019, the FDA approved Johnson & Johnson’s isolated formulation of the ketamine molecule, esketamine (sold under the brand name Spravato as a nasal spray), for treatment-resistant depression ...

Le Daré B, Pelletier R, Morel I, Gicquel T. (2022) Histoire de la kétamine : une molécule ancienne qui a toujours la cote [History of Ketamine: An ancient molecule that is still popular today ...

My psychiatrist recommended ketamine — specifically, Spravato, an FDA-approved nasal spray that administers eskatamine, a mirror image of the ketamine molecule. (The other option was to have a ...

Racemine ketamine: Usually given intravenously, it was approved by the FDA decades ago for use as an anesthetic, Harvard Medical states. It is a molecule mixture of "R" and "S" ketamine.