Opioid overdoses are a major public health issue in the U.S., killing tens of thousands of people every year. The medicine ...

Pharmacokinetic rationale of intraperitoneal therapy Intraperitoneal (IP) therapy represents a logical alternative means to deliver high drug concentrations to tumors located in the peritoneal ...

Understanding how drug delivery systems distribute in vivo remains a major challenge in developing nanomedicines. Especially ...

February 13, 2014 -- Until now, IP cores delivered to customers were mainly targeted for in-flight applications. This means that no errors are allowed to be generated from the system. However, a ...

To address these issues, a novel data-driven model, named MaskScoreNet-E ... we proposed a region-adaptive thresholding segmentation (RATS) algorithm that combines target depth-based greyscale ...

We investigated the effect of ERR agonist on cardiac function in a pressure overload–induced HF model in vivo. We conducted comprehensive ... This may also be attributed to differences between rat and ...

The assembled capsule was further tested in vivo to validate the actuation sequence and showed a 70% (n = 17) success rate in an animal model. Additionally, a drug delivery study indicated systemic ...

HES can improve mitochondrial malfunction during benzopyridine-induced lung carcinogenesis in a mouse model; for example, it upregulates antioxidant and TCA cycle enzymes, protects electron transport ...