We present a robust and simple method for direct, label-free PCR product quantification using an integrated microelectronic sensor. The field-effect sensor can sequentially detect the intrinsic charge ...

Nucleic acids (DNA or RNA) are polymers of nucleotides – each nucleotide consists of a pentose sugar, a phosphate group and one of the nitrogenous bases (purines and pyrimidines). Nucleic acids ...

Nucleic acid therapeutics are based on nucleic acids or closely related chemical compounds. They include antisense oligonucleotides, aptamers and small interfering RNAs, and are typically ...

Quantifying the hydropathy of nucleic acids presents unique challenges due to their chemically distinct components (nitrogenous bases, pentose sugars, and charged phosphate groups) connected via ...

Overview The research laboratory of Louis (Jim) J. Maher III, Ph.D., studies the nucleic acids DNA and RNA. Dr. Maher's research team works to understand how the locally stiff DNA molecule is bent and ...

Is the most recent removal methods for the effects of Acid Orange 7 (AO7) dye colour from wastewater have complied. Microbial biodegradation, chemical decomposition by oxidation, photo-degradation and ...

Keywords: Bioorganic chemistry, fluorescent dyes, DNA nanotechnology, molecular evolution, peptide nucleic acids, molecular recognition of DNA/RNA, G quadruplexes The Armitage group designs and ...