Our prior implementation of the assay relied on an intercalating dye to provide nonspecific fluorescence when bound to double-stranded DNA (dsDNA) synthesized by HIV RT. For drugs like TFV-DP that ...

Bridged nulceic acids increase the stability of DNA scaffolds carrying cyanine dye Cy5 aggregates. In addition, the presence of bridged nucleic acids in the scaffold increase the coupling strength ...

Future Virology. 2008;3(2):179-192. Although not listed as a hemorrhagic fever virus, illness caused by CHIKV can be confused with diseases such as dengue or yellow fever, based on the similarity ...

COVID-19 pandemic ignited the development of countless molecular methods for the diagnosis of SARS-CoV-2 based either on nucleic acid, or protein analysis, with the first establishing as the most used ...

The Nucleic Acids Institute is dedicated to understanding the chemical and biological basis for nucleic acid function, and to developing new and powerful nucleic acids based therapeutic and ...

Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, Indiana 47907, United States Birck Nanotechnology Centre, Purdue University, West Lafayette, Indiana 47907, ...

Beckwith-Wiedemann syndrome (BWS) is a human genomic imprinting disorder that presents with a wide spectrum of clinical features including overgrowth, abdominal wall defects, macroglossia, neonatal ...