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This important work offers a fresh perspective central to merozoite surface biology and potential implications on vaccine design, challenging the dogma that MSPs are indispensable invasion engines.
Antimicrobial peptides are important components of the host innate immune system, forming the first line of defense against infectious microorganisms. Among them, liver-expressed antimicrobial ...
Most responses induced in response to many polymorphic targets may not be protective and act as a 'smoke-screen', and hypergammaglobulinemia, a common feature of P. falciparum infection, may ...
Plasmodium falciparum uses RIFIN proteins to bind to the inhibitory receptor KIR2DL1 on natural killer (NK) cells, thereby evading their attack. Conversely, NK cells can recognize RIFIN via the ...
ORIGINAL RESEARCH article Front. Immunol. Sec. Viral Immunology Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1584785 This article is part of the Research Topic Antiviral Innate Immune Mechanisms in ...
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