A new review sheds light on the complex molecular mechanisms behind Angelman syndrome (AS), a rare neurogenetic disorder, and ...

Background/aim Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are rare imprinting disorders caused by the aberrant ...

Ionis has committed to a phase 3 programme for its antisense therapy for rare genetic disorder Angelman syndrome, just weeks after Biogen decided against exercising an option to license the drug.

Some imprinted genes might be associated with a risk of neuropsychiatric disorders, notably autism spectrum disorders and the phenotypically overlapping conditions Angelman syndrome and Rett syndrome.

Symptoms of Werner syndrome, which causes premature aging, can appear in a person's teens and progress quickly in their 20s ...

“Angelman syndrome is a genetic development disability,” said Dr. Wendy Pierce, Pediatric Rehabilitation and Medicine Specialist at Children’s Hospital Colorado.

The firm expects to complete enrolling the REVEAL trial, in which patients will receive the ASO, dubbed ION582, in 2026.

While people who have a family history of type 1 diabetes may be predisposed to developing it, the inheritance pattern in most cases is unclear. Type 2 diabetes results when the body doesn’t use ...

“Finally, they did a neurological test and then they did some genetic testing, and then that’s when they realized, okay, he’s got Angelman syndrome,” said Emanuel. Finally, the Prodans had ...

Angelman syndrome ( AS) is a neurodevelopmental disorder characterised by severe learning difficulties, ataxia, a seizure disorder with a characteristic EEG, subtle dysmorphic facial features, and a ...