The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, United States ...

In this review, we examine the effects of HIV‐associated inflammation and immune activation on the cardiovascular system with a focus on atherosclerotic CVD and discuss existing and proposed ...

It is possible that the broadness of colchicine effects (affecting various pathways of the inflammatory processes) is an advantage in the complex pathophysiological interplay between inflammation, ...

In contrast, alprazolam did not activate this inflammation pathway. In fact, it reduced the amount of a harmful molecule called IL-6, which is also linked to tumor growth and inflammation.

Conclusion Early-career elite athletes showed increased markers of air pollution exposure, epithelial damage and airway inflammation compared with controls. Acute exposure to increased air pollution ...

10.1111/j.1365-313X.2004.02016.x MAPMAN is a user-driven tool that displays large data sets onto diagrams of metabolic pathways or other processes. SCAVENGER modules assign the measured parameters to ...

This package lets you generate entity relation diagrams by inspecting the relationships defined in your model files. It is highly customizable. Behind the scenes, it uses GraphViz to generate the ...

The latest therapeutic approaches now being investigated in clinical trials include mainly targets of T cells differentiation, inflammatory pathways, inhibition of adhesion molecules and innate immune ...