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Hosted on MSN9h
Immune cell inflammation may be responsible for some severe symptoms in lysosomal storage diseases
We are continuing to explore how the lysosome regulates macrophage function and inflammation in LSDs and other conditions ...
Key mechanisms of enzyme involved in rare metabolic disease identified
An international research team has published a study in the journal The FEBS Journal that significantly advances the ...
News-Medical.Net on MSN2d
ADA2 regulates inflammation through lysosomal and extracellular mechanisms
Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and activation. Unlike ADA1, which primarily functions intracellularly, ADA2 can be ...
thorax.bmj2d
The changing face of inflammation following CFTR modulation: identifying new phenotypes of innate immunity
Much attention has been paid to ETI’s effects on clinical parameters and pulmonary inflammation and infection, but fewer studies have focused on the effects of ETI on systemic inflammation. Comparing ...