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Researchers used advanced microscopy to uncover important protein structures. For the first time, two important protein ...
Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These ...
Role of Chaperones in Muscle Function. To ensure proteins achieve their correct shape, cells use specialized molecular assistants called chaperones. These chaperones act as caretakers, helping ...
Predicting proteins’ structure from their amino acid sequences had stumped researchers since the 1970s. But in 2020, Hassabis and Jumper developed an artificial intelligence model called AlphaFold2.
But predicting a single protein structure is only half of the problem. In the real world, proteins work together as molecular machines that carry out complicated biological functions.
Designing proteins that can change their structure, and ultimately function, in response to specific molecular signals, a phenomenon known as allosteric regulation, has been a long-standing goal ...
During this period, animals rely on the fat stores they’ve built up over the previous months to sustain their bodily functions. ... Myosin protein structure was not found to differ in active and ...
Image credit: Ole Frøbert, Aarhus University, Denmark . Their research, in small and large hibernating mammals, is described by the editors as an important study advancing our knowledge of the role of ...
Actin-binding proteins account for 20% of the total cellular proteins that can bind actin and regulate the functions of actin filaments. Accompanying the evolution of actin during three billion years, ...
Proteins are vital for constructing and maintaining the body's structures, acting as building blocks. They help in tissue formation, growth, repair, and essential functions.
An AI called AlphaFold predicted structures for nearly every protein known to science. Those predictions aren’t without limits, some researchers say.