Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to ...

Symmetry is a fundamental characteristic of most multi-cell animals. However, the cell division of embryonic cells is ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

A paper titled "Functional implications of unusual NOS and SONOS covalent linkages found in proteins," by Matthew D. Lloyd, ...

Our new images reveal human PINK1 sitting on a composition of pores arranged symmetrically on the surface of the mitochondria. This arrangement is more elaborate than anyone had anticipated and even ...

The F-actin based motor protein myosin II has ... We conclude that the sole essential function of RLCs in fission yeast is to relieve the auto-inhibition of myosin II function, which is mediated ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre-Cebollada, has developed an ...

Findings suggest that slack titin molecules drive muscle disease, potentially through mechanisms shared with other mechanical ...

Many of the proteins that ... any physiological function of this signaling complex independent of localization. Here we demonstrated that INAD bound directly to the NINAC myosin III, yet the ...

PME-1 is a protein that modifies other proteins by ... "Additionally, this study highlights the importance of activity–independent functions of enzymes, which may have been overlooked in ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...