The genetic disease harlequin ichthyosis affects the transport of fats within the skin, resulting in hard, scalelike plaques and an array of other symptoms.

Suicide rate increased 60% since 2011 among US youth and young adults: CDC report The rate rose from 6.9 per 100,000 in 2001 to 11 per 100,000 in 2021.

Subsequently, the patient treated both heels with salicylic acid 6% multivesicular cream. A second patient, a 25-year-old woman, was treated for ichthyosis vulgaris and hyperkeratosis of both heels.