This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Considering that MMD is mostly sporadic and gene-environment interactions play an important in various diseases, we sought to investigate epigenetic modifications in MMD, focusing specifically on ...

Aberrant RUNX1 methylation and reduced expression are characteristic of type 1 autoimmune pancreatitis (AIP), a form of IgG4-related disease. All patients with AIP exhibited lymphoplasmacytic ...

Dendritic cells (DCs) are critical in the maintenance of self-tolerance and altered functions of DCs have been implicated in the pathogenesis of a number of autoimmune diseases, such as rheumatoid ...

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

leading to higher rates of certain autoimmune disorders(1 Trusted Source The risk of immune-mediated inflammatory diseases following exposure to childhood maltreatment: A retrospective ...

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to ...

Is IBD an autoimmune disease? While it has similarities with autoimmune diseases, IBD is a little different. IBD falls under the umbrella of immune-mediated inflammatory diseases (IMIDs).

Video: Broad Institute of MIT and Harvard At a glance: Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though patients are born ...