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Epigenetic features refer to DNA methylation and hydroxymethylation, histone modifications, and non-coding RNAs, which all contribute to play a role in the development of autoimmunity. In the last few ...
A recent review by Prof. Zhu Bing and Associate Professor Xiong Jun from the Institute of Biophysics of the Chinese Academy ...
Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...
Cardiometabolic disease, emerging as a worldwide epidemic, is a combination of metabolic derangements leading to type 2 diabetes mellitus and cardiovascular disease. Genetic and environmental factors ...
Similar to classical histone modifications such as acetylation and methylation, lactylation is integral to various physiological and pathological processes by influencing chromatin structure and gene ...
Epigenetics involves a series of biological processes that regulate chromatin-mediated DNA templates. 2 Cancer is a ...
Women are up to four times more likely than men to be affected by autoimmune disease, conditions in which the immune system mistakenly attacks the body's own cells.
S L E is a complex autoimmune disease that results from the interplay of genetics, epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism that regulates gene expression ...
Citation Format: Ying-Yu Chen. Modulating DNA and histone methylation as a therapeutic target for non-small cell lung cancer by shifting the composition of immune cells [abstract]. In: Proceedings of ...
For more than a decade, genome-wide association studies have been applied to autoimmune diseases and have expanded our understanding on the pathogeneses. Genetic risk factors associated with diseases ...