This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Dendritic cells (DCs) are critical in the maintenance of self-tolerance and altered functions of DCs have been implicated in the pathogenesis of a number of autoimmune diseases, such as rheumatoid ...

Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

The paper titled "Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models," appeared recently in the Journal of Clinical Investigation. Xian C.

Auto-immune and inflammatory diseases are heterogenous in their clinical manifestations and prognosis, even among individuals presenting with the same pathology. Understanding the immunological ...

leading to higher rates of certain autoimmune disorders(1 Trusted Source The risk of immune-mediated inflammatory diseases following exposure to childhood maltreatment: A retrospective ...

Scientists at the Garvan Institute of Medical Research have discovered how a viral infection causes autoimmune disease, disproving a long-standing theory and opening a promising new approach to ...

Request permissions for this article. Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (A.P.H., M.S., M ...