Many people with autoimmune diseases are initially misdiagnosed with psychiatric conditions. Here’s why you shouldn’t accept ‘it’s all in your head’ for an answer.

Epigenetic mechanisms, including DNA methylation and histone modifications, control regional chromatin structure and thereby influence gene expression. In this Review, Dr Richardson discusses the ...

Epigenetic features refer to DNA methylation and hydroxymethylation, histone modifications, and non-coding RNAs, which all contribute to play a role in the development of autoimmunity. In the last few ...

A recent review by Prof. Zhu Bing and Associate Professor Xiong Jun from the Institute of Biophysics of the Chinese Academy ...

Histone deacetylase inhibitors (HDAC inhibitors, HDACi) have garnered considerable attention due to their potential in treating various types of malignant tumors. Histone deacetylases (HDACs) not only ...

A large UK study has found that people living with autoimmune diseases are nearly twice as likely to experience long-term mental health problems such as depression, anxiety, and bipolar disorder ...

Cue Biopharma receives positive FDA feedback on CUE-401, a novel T cell modulator for autoimmune disease treatment.

In addition to summarizing advances in histone Kla, this review is among the first to systematically dissect the molecular mechanisms, functional roles, and disease relevance of non-histone Kla ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...