gut.bmj3d
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade
Here, we describe the contribution of hepatocyte ferroptosis to CD8 + T cell activation ... expert technical assistance as well as the staff at the Animal Facility and the Histology and Flow Cytometry ...
Nature5d
Non-alcoholic fatty liver disease articles from across Nature Portfolio
Non-communicable diseases represent the primary cause of mortality and morbidity globally, accounting for 74% of all deaths and more than three-quarters of years lived with disability. Here, we ...
gut.bmj5d
Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype
coli indirectly enhance tumour growth by inducing the emergence of senescent cells secreting growth factors. The hepatocyte growth factor (HGF) is the main mechanistic link between pks+ E.
Frontiers5d
Long-Term Liver Expression of an Apolipoprotein A-I Mimetic Peptide Attenuates Interferon-Alpha-Induced Inflammation and Promotes Antiviral Activity
Apolipoprotein A-I mimetic peptides are amphipathic alpha-helix peptides that display similar functions to apolipoprotein A-I. Preclinical and clinical studies have demonstrated the safety and ...
Frontiers6d
A Systematic Study of the Mechanism of Acacetin Against Sepsis Based on Network Pharmacology and Experimental Validation
Acacetin (MedChemExpress, molecular weight: 284.26 g/mol), LPS (Sigma, 055:B5, L2880), and Gap27 (MedChemExpress) were used in the experiments. The lung and liver tissues were collected and fixed in a ...