We report the discovery of GTP-state-selective cyclic peptide ligands of K-Ras (G12D), a prevalent oncogenic driver, using an integrated in vitro translation−mRNA display selection platform.

Floods have been considered amongst the most recurring and devastating natural hazard types as they result in extensive economic losses to humans and infrastructures worldwide. Maysan city in southern ...

Revolution Medicines and Summit Therapeutics Enter into Clinical Collaboration to Evaluate Combinations of Three RAS (ON) Inhibitors with Ivonescimab in RAS Mutant Tumors ...

Revolution secured the funding infusion from Royalty in return for a slice of the profits if Revolution's lead cancer drug makes it to market.