The Royal Society of Chemistry has signed the San Francisco Declaration on Research Assessment (DORA), continuing our drive to modernise how we measure excellence in the chemical sciences. We are the ...

We performed a phase 3 trial involving women 18 to 70 years of age with moderate-to-severe vasomotor symptoms associated with endocrine therapy for HR-positive breast cancer or its prevention.

Vepdegestrant is an oral proteolysis-targeting chimera (PROTAC) estrogen receptor (ER) degrader that directly harnesses the ubiquitin–proteasome system.In this phase 3, open-label, randomized ...

Objective To develop sex-specific and age-specific normative values for the nine Eurofit tests in European children and adolescents aged 9–17 years. Methods A systematic review was undertaken to ...

Objective To examine whether the associations between sedentary behaviours (ie, daily sitting/TV-viewing time) and mortality from cardiovascular disease (CVD) and cancer differ by different levels of ...

Abstract: Interactive history tools, ranging from basic undo and redo to branching timelines of user actions, facilitate iterative forms of interaction. In this paper, we investigate the design of ...

Abstract: A method for recognizing characters on graphical designs is proposed. A new projection feature that separates text-line regions from backgrounds, and adaptive thresholding in displacement ...

Objectives Implementation studies are often poorly reported and indexed, reducing their potential to inform the provision of healthcare services. The Standards for Reporting Implementation Studies ...

This study presents the first comprehensive assessment of the global burden of AMR from 1990 to 2021, with results forecasted until 2050. Evaluating changing trends in AMR mortality across time and ...

Data extraction is the process of a systematic review that occurs between identifying eligible studies and analysing the data, whether it can be a qualitative synthesis or a quantitative synthesis ...

Of the 7763 records identified, nine reviews were eligible for inclusion of the umbrella review. One review was judged to be of moderate quality, while the others were either low (n = 3) or critically ...