An uncharacterized chromatin factor ZNF280A is recruited to sites of DNA damage. Credit: Nature Cell Biology (2025). DOI: 10.1038/s41556-025-01674-1 ...

The research is published in the journal Nature. The study comprehensively analyzed "cis-regulatory elements" (CREs), which are the DNA sequences that regulate gene transcription.

Researchers have revealed a new mechanism underlying how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer ...

As the first crystal structure of this type, the researchers say it will also be useful as a model for other targets in the genome, besides the insulin gene, which form this shape of DNA.

Crucially, the researchers discovered both loops of RNA can be reprogrammed. That means scientists can specify a genomic location as well as what sequence should go there. In theory, the system could ...

Number of gene therapy clinical trials approved worldwide 1989-2017 Ginn SL, Amaya AK, Alexander IE, Edelstein M, Abedi MR. Gene therapy clinical trials worldwide to 2017: An update. J Gene Med ...

graph theory 1 Articles Where Graph Theory Meets The Road: The Algorithms Behind Route Planning April 4, 2024 by Maya Posch 33 Comments ...

Gene therapies treat or prevent disease by tweaking the content or expression of cells' DNA. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works ...

Currently, many clustering algorithms are applied in gene expression analysis. Nevertheless, owing to the high dimensionality of gene expression data, many algorithms face the problem of low ...