For example, monocytes and M2 macrophages show increased fatty acid oxidation and oxidative phosphorylation, whereas M0 and M1 macrophages show increased glycolysis. This means that investigating the ...
Because reactive oxygen species are produced via oxidative phosphorylation during anaerobic glycolysis, via the Schiff reaction during glycation, via glucose autoxidation, and via hexosamine ...
To produce energy, normal cells typically go through a process that starts with glycolysis (the breaking down of glucose, or sugar) and ends with oxidative phosphorylation. In 1931, Otto Heinrich ...
RNA-seq and MS analyses indicated that L-arginine switched glycolysis to oxidative phosphorylation in inflammatory osteoclasts leading to increased ATP production, purine metabolism and elevated ...
Metabolic reprogramming also contributes to this process, with M1 macrophages prioritizing glycolysis while M2 macrophages utilize oxidative phosphorylation. Redressing this imbalance by modulating ...
Loss of SMAD4 induces PGK1 upregulation in PDAC, which enhances glycolysis and aggressive tumour behaviour. Notably, in SMAD4-negative PDAC, nuclear PGK1 preferentially drives cell metastasis via ...
DNA-replication genes were also inhibited (p=0.002), (figure 6B). Gene sets enriched in HAMLET-treated tumours included oxidative phosphorylation (p=0.001) and glycolysis (p=0.013) as well as ...
Figure 3 Main metabolic pathways in T cells. T cells generate ATP by glycolysis and oxidative phosphorylation. Pentose phosphate pathway (PPP) is a branch of glycolysis pathway. Cells also generate ...
2d
News Medical on MSNPAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosisEndometriosis, a prevalent gynecological condition, is characterized by the growth of endometrial-like tissues outside the ...
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