Abstract Abstract Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency, recognized as the most prevalent enzymopathy globally, limits pentose phosphate pathway (PPP), causing oxidative ...

Researchers have uncovered how the breakdown of glycogen may protect the brain from neurodegeneration and Alzheimer's.

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

Abstract TREATMENT of infection often necessitates the use of drugs that can cause hemolytic reactions in patients with erythrocytes deficient in glucose-6-phosphate dehydrogenase (G-6-PD).

G6PD, expressed in all of the body's tissues, controls the flow of carbon through the pentose phosphate pathway, produces NADPH for reductive biosynthesis, and maintains oxidation-reduction in the ...

Engineering strategies to improve terpenoids’ production in Bacillus subtilis mainly focus on 2C-methyl-d-erythritol-4-phosphate (MEP) pathway overexpression. To systematically engineer the chassis ...

Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the ...

Introduction Plasmodium vivax is the predominant cause of malaria in the Greater Mekong Subregion. To ensure safe treatment with primaquine, point-of-care glucose-6-phosphate dehydrogenase (G6PD) ...

Favism is a severe, acute haemolytic anaemia which occurs in about 20% of G6PD deficient subjects after ingestion of fava beans. Since not all G6PD deficient subjects are sensitive to fava beans, the ...