Fatty acids serve as energy stores, building blocks for biological membranes, or cellular messenger substances. In yeast and higher organisms, FAS forms a higher order structure of several enzymes.

Fatty acids serve as energy stores, building blocks for biological membranes, or cellular messenger substances. In yeast and higher organisms, FAS forms a higher order structure of several enzymes.

Rather than using a conventional type I or II fatty-acid synthase,Trypanosoma bruceisynthesize most of their fatty acids by an unprecedented mechanism. Here, Paul Englund and colleagues describe ...

Fatty acid synthase (FAS) is the key enzyme of de novo fatty acid synthesis and has been shown to be involved in carcinogenesis of numerous human malignancies, including breast, colorectal, and ...

Fatty acids are essential in all living organisms: to store energy, form membranes, and multiply. They are produced by a complex cellular machinery – the fatty acid synthase. A team of the Max Planck ...

Max Planck researchers discover first protein that regulates fatty acid synthase. This opens the prospects in medicine and in ‘green biotechnology’.

According to a recent report from the World Health Organization, it can be estimated that worldwide about 250 million adults — 7 percent of the population — are obese, defined as having a body ...

BJT-188 is a preclinical, liver-targeted fatty acid synthase (FASN) inhibitor currently under investigation by Bluejay Therapeutics for the treatment of metabolic dysfunction-associated ...

Fatty acid synthase (FASN) can act as a prostate cancer oncogene in mouse models.

Fatty acid synthase (FASN) regulates de novo lipogenesis, body weight, and tumor growth. We examined whether common germline single nucleotide polymorphisms (SNPs) in the FASN gene affect prostate ...

18185 Fatty acid synthase (FAS) is highly expressed in many human cancers, including lung cancers. Previous work has shown that blocking FAS activity by cerulenin, a natural antibiotic, or C75, a ...

TVB-2640, a fatty acid synthase inhibitor, significantly reduced liver fat and serum biomarkers of liver injury, fibrosis and inflammation in patients with nonalcoholic steatohepatitis according ...