Context: Fatal familial insomnia (FFI) is a genetically transmitted neurodegenerative prion disease that incurs great suffering and has neither a treatment nor cure. The clinical literature is ...

DF was a right-handed, 52-year-old, white, American man with a doctorate in naturopathy. DF's father, paternal uncle, and 2 male cousins were diagnosed with fatal familial insomnia (FFI). His ...

Fatal familial insomnia (FFI) starts out with mild insomnia but progresses quickly, eventually leading to a complete inability to sleep.

Sleep is essential for our physical and mental well-being. And, yet, the Sleep Foundation estimates that 50 to 70 million people in the US alone experience sleep disturbances, with insomnia, sleep ...

That’s what happens in cases of fatal familial insomnia. FFI is a degenerative brain disorder that causes people to lose their ability to fall asleep.

Fatal familial insomnia is a rare brain disorder that targets the brain and nervous system, which can be life-threatening.

The most notable FFI symptom is insomnia or being unable to fall or stay asleep. The symptoms worsen with the passage of time and at one point, the patient cannot sleep at all.

As fatal familial insomnia progresses, patients completely stop sleeping and enter a coma-like state that results in death within months.

Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of ...

"Don't Know How Long I Have": 25-Year-Old With Undiagnosed Neurological Disease The user shared their journey with the disease, which they've been told is similar to rare Fatal Familial insomnia ...

As the Cleveland Clinic explains, Fatal Familial insomnia “is a rare genetic condition that causes sleeping difficulties (insomnia), memory loss (dementia) and involuntary muscle twitching.