Scientists have uncovered how a surprisingly structured protein helps disordered molecules regulate gene expression, upending previous ideas in molecular biology. Inside every human cell, proteins ...

New research suggests that DNA sequences historically considered to be "junk" have had an overlooked role in gene expression ...

A portion of our genome that was once dismissed as being “junk” may actually play an important role in regulating gene ...

A recent study characterized the expression of ADC targets across ovarian cancer histotypes. Findings suggest ...

ALKBH1 is a genomic DNA 6mA demethylase that preferentially removes 6mA in bubbled/bulged DNA and ssDNA, instead of dsDNA.

Although outbreaks of Ebola virus are rare, the disease is severe and often fatal, with few treatment options. Rather than ...

Across two new papers published Wednesday (July 23) in the journal Nature, scientists sequenced the DNA of 1,084 people ...

Vabametkib in MET exon 14 skipping non-small-cell lung cancer: Efficacy and safety from the open-label, phase 2, cohort-1 trial.

In a phase 1–2, multinational, open-label study, we enrolled nine children who had severe LAD-I and treated them with marnetegragene-autotemcel (marne-cel), a gene therapy of autologous CD34 ...

Exon 1 deletion of the androgen receptor gene causing complete androgen insensitivity syndrome in a newborn: a case report Shengxia Wang † Ya-Ting Zhang † Fan Wang* Department of Neonatology, The ...

Understanding sickle cell disease Sickle cell disease is caused by a mutation in the HBB gene, which encodes the beta-globin subunit of hemoglobin. This mutation results in the production of ...

ATLANTA, Dec. 11, 2024 /PRNewswire/ -- Expression Therapeutics, Inc., has presented the results of a Phase 1 clinical trial for its novel lentiviral vector-based gene therapy — ET3 — for hemophilia A ...