News

Optimizing enzyme inhibition analysis with one experiment instead of dozens
A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction ...
Nature3d
Enzyme mechanisms articles from across Nature Portfolio
Enzyme mechanisms are the chemical transformations ... the very different H3K4 and H3K36 substrates by distinct substrate interaction modes. Our data illustrate evolutionary pathways for ...
Nature3d
Directed evolution of the surface chemistry of the reporter enzyme β-glucuronidase
The use of the Escherichia coli enzyme β-glucuronidase (GUS) as a reporter in gene expression studies is limited due to loss of activity during tissue fixation by glutaraldehyde or formaldehyde.
Natural Science News3d
How A Protein Works With An Enzyme To Build Germs' Outer Layer
Scientists discovered a key protein, MigC, that helps a dangerous superbug, *A. baumannii*, build its protective outer layer ...
C&EN2d
Between Protein Fold and Nucleophile Identity: Multiscale Modeling of the TEV Protease Enzyme–Substrate Complex
Views diverge on what protonation state is characteristic of catalytic Cys and His at the Michaelis (enzyme–substrate) complex of TEVp and ... through a tetrahedral intermediate stabilized by ...
C&EN3d
Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase
Get article recommendations from ACS based on references in your Mendeley library. Pair your accounts. Export articles to Mendeley Get article recommendations from ACS based on references in your ...