Figure 5: Standard view from the μPl substrate towards the active site of the μPl enzyme in complex with SAK (shown as a solid surface). The overall structure of the cleaved μPl substrate is ...

The molecules that form the foundation of life on Earth are as diverse as they are complex. Among these, carbohydrates play a ...

Considering the geometry of such an enzyme-substrate-complex, they identified three golden rules that should be considered to build a functional enzyme. First, the interface of both enzyme and ...

A team of researchers, led by Professor Chae Un Kim from the Department of Physics at UNIST, has successfully tracked the catalytic pathway of carbonic anhydrase II (CAII), an enzyme that converts ...

NCoR1/RARα interaction was identified as a target for selective chaperone-mediated autophagy (CMA) inhibition in lung cancer.

Kapoor and colleagues have only looked at the two enzymes interacting on their own, without a tagged substrate present. In ...

Views diverge on what protonation state is characteristic of catalytic Cys and His at the Michaelis (enzyme–substrate) complex of TEVp and related proteases. (23) It is not a cosmetic difference, ...