This paper reports on a correlation between diminished cardiolipin content and the severity of steatohepatitis in human subjects. This is supported further by experimental evidence from mice in which ...

As they spread, these enzymes can hydrolyze distant substrates, but hydrolysis products may not be ... All chemicals were obtained from Sigma-Aldrich (United States). The cluster diagram, non-metric ...

Considering the geometry of such an enzyme-substrate-complex, they identified three golden rules that should be considered to build a functional enzyme. First, the interface of both enzyme and ...

A microscopic enzyme could be the key to helping nitrogen fertilizers stick better to the soil and prevent runoff that causes ...

Computer algorithms have designed highly efficient synthetic enzymes from scratch, with minimal need for tedious hands-on ...

Interestingly, the sugar-cleaving enzyme was detected in the cell nucleus, while the substrate is thought to be located in the vacuole. After the sugar has been cleaved, the substances are highly ...

Many chemical reactions require the input of energy to activate the transformation. This can often be in the form of heat, or ...

The molecules that form the foundation of life on Earth are as diverse as they are complex. Among these, carbohydrates play a ...

This process of looking and asking questions about what you are looking at is needed at all levels of science, and science ...

NCoR1/RARα interaction was identified as a target for selective chaperone-mediated autophagy (CMA) inhibition in lung cancer.

(18) Intriguingly, no significant conformational changes of the enzyme were observed between the initial and final states, with the corresponding crystal structures being mostly identical, apart from ...