News

Unlocking the secrets of enzyme catalysis: Researchers capture molecular movie of carbonic anhydrase II in action
A team of researchers, led by Professor Chae Un Kim from the Department of Physics at UNIST, has successfully tracked the ...
Nature4d
‘Remarkable’ new enzymes built by algorithm with physics know-how
Computer algorithms have designed highly efficient synthetic enzymes from scratch, with minimal need for tedious hands-on ...
Optimizing enzyme inhibition analysis with one experiment instead of dozens
A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction ...
Engineered enzyme enables detailed mapping of tRNA changes in tumor cells
An engineered enzyme is at the center of a new method to visualize molecular details in human cells, and how these molecules ...
C&EN5d
Coordinated Residue Motions at the Enzyme–Substrate Interface Promote DNA Translocation in Polymerases
(18) Intriguingly, no significant conformational changes of the enzyme were observed between the initial and final states, with the corresponding crystal structures being mostly identical, apart from ...
C&EN3d
Between Protein Fold and Nucleophile Identity: Multiscale Modeling of the TEV Protease Enzyme–Substrate Complex
Views diverge on what protonation state is characteristic of catalytic Cys and His at the Michaelis (enzyme–substrate) complex of TEVp and related proteases. (23) It is not a cosmetic difference, ...