A recent study published in eLife offers a new perspective on the development of Alzheimer’s disease, suggesting that the ...

Researchers have expanded the colour palette of bioluminescent protein to 20 distinct colours, enabling advanced simultaneous multicolour imaging.

For years, scientists have focused on amyloid beta buildup as the main culprit in Alzheimer’s disease, but a new study suggests the real problem might lie in a stalled protein-cutting process in the ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

A latest research reported in Engineering reveals that researchers from Fuzhou University and Hunan Agricultural University ...

Department of Chemistry, Engineering Center of Catalysis and Synthesis for Chiral Molecules, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China Shanghai Engineering Research Center of ...

Bioluminescence, the natural emission of light by living organisms, is powered by a chemical reaction catalyzed by an enzyme, typically a luciferase, acting on a bioluminescent substrate.

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. The research, published today in eLife, is described by editors as a fundamental study ...

"These findings are in keeping with our 'stalled complex' hypothesis, where it is these enzyme-substrate complexes that trigger neurodegeneration even in the absence of amyloid beta-protein ...