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Nature Reviews Gastroenterology & Hepatology - Gut endothelial cells — another line of defence. ... endothelial cells in the GVB expressed a number of tight junction and adherens junction proteins.
As a result, the endothelial cells themselves are responsible for determining which molecules pass from the gut lumen into the surrounding tissues. ... adhesive junctions attach cells to the ECM.
Jianmin Yin et al, Oscillatory contractile forces refine endothelial cell-cell interactions for continuous lumen formation ...
Since the emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), understanding the mechanisms underlying ...
(PhysOrg.com) -- University of Pennsylvania bioengineers have demonstrated that the cells that line blood vessels respond to mechanical forces -- the microscopic tugging and pulling on cellular ...
Adherens junctions, the structures that allow cohesion between cells in a tissue, appear to be modulated by endothelial cell-to-cell tugging forces.
They genetically labeled blood vessel endothelial cell tight junctions with a fluorescent protein to examine if and how tight junctions are involved in autoimmune encephalomyelitis in vivo in ...
The findings are published in Proceedings of the National Academy of Sciences in an article titled, “A 3D biomimetic model of lymphatics reveals cell–cell junction tightening and lymphedema ...
If Raf-1 is not present, the cells cannot stick together and the formation of new blood vessels is inhibited. This discovery may one day lead to new approaches to cancer treatment.
Researchers at VCU Massey Comprehensive Cancer Center and the VCU Institute of Molecular Medicine (VIMM) have discovered a ...
Some Aβ can pass through the blood-brain barrier via active transport across endothelial cells (see Deane et al., 2003; Deane et al., 2004). On the other hand, it is still unclear whether Aβ can also ...
Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification. Haematopoietic stem and progenitor cells ...