One of the main factors determining therapeutic antibodies’ half-life is the interaction between the antibody’s Fc region and ...

In the realm of peptide-based research, few compounds have garnered as much interdisciplinary interest as BPC-157. This ...

Solar cells and computer chips need silicon layers that are as perfect as possible. Every imperfection in the crystalline ...

The Kennedy College of Science, Department of Chemistry, invites you to attend a Ph.D. Dissertation defense by Sabrina Apel entitled “Biophysical Characterization of the Interaction Between S100A1 and ...

Though not a mutual defense alliance, the Shanghai Cooperation Organization (SCO) remains the most important multilateral ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

Having shown that the interaction of the Ena/VASP-EVH1 domain with WAVE2 is relevant for actin polymerization velocity, chemotaxis, extravasation, and MDA-MB-231 breast cancer metastasis in vivo, we ...

The interaction surface is highly conserved between MUC5AC-D3 and MUC2-D3 with only three relevant substitutions. In the C8-3 domain interaction region MUC5AC-D3 presents a phenylalanine (Phe1086, Fig ...

Woo, J.R., Bae, S., Wales, T.E., Engen, J.R., Lee, J., Jang, H., et al. (2024) The Serine Phosphorylations in the IRS-1 PIR Domain Abrogate IRS-1 and IR Interaction ...

Existing classifications of human-AI interactions are often domain-specific, lacking a comprehensive framework that spans multiple domains. Without a shared vocabulary to describe human-AI ...

In myocilin-associated glaucoma, pathogenic missense mutations accumulate mainly in the olfactomedin domain (mOLF) of myocilin. This makes the protein susceptible to aggregation, where mOLF–mOLF ...