for instance by involving a combination of several different types of catalysis. Determining enzyme mechanisms includes determining their kinetic and thermodynamic properties. Structures ...

When someone has high blood pressure, or hypertension, it results in changes to the walls of their blood vessels. This ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

In a collaborative effort, researchers at the University of Amsterdam and the HFML-FELIX institute in Nijmegen have been able ...

"As an FXR agonist, [it] has a different mechanism of action from other treatments and is backed by a wealth of positive real-world evidence, gathered from more than seven years of clinical use.

†This work was supported by NIH Grant GM-41574 (V.L.D.). * To whom correspondence should be addressed: Department of Biochemistry, University of Mississippi Medical Center, 2500 N. State St., Jackson, ...