DSS-induced acute colitis is largely mediated by macrophages, so any manipulation associated with less severe inflammation is accompanied by lesser macrophage infiltration in this model: this does not ...

Results By comparing the immune and inflammatory responses between wt and CD131-deficient mice, we found that CD131 contributed to DSS-induced murine colitis, which functioned in synergy with tissue- ...

This study presents evidence that dextran sulfate sodium (DSS)-induced colitis exacerbates periodontitis through the activation of the NADPH oxidase 2 (NOX2)/reactive oxygen species (ROS) axis in ...

ARS alleviated DSS-induced murine colitis by regulating macrophage polarization via inhibiting ERS. (A, B) FCM detection (CD86 + and CD206 +) and data analysis of colonic macrophages.

Researchers from Ocean University of China and Qingdao Marine Science and Technology Center published data from a preclinical study that investigated the impact of the quinazolinone derivative MR-2938 ...

Bear bile powder inhibits the release of NLRP3 by activating the cAMP/PKA/CREB signaling pathway to treat dextran sulfate sodium-induced colitis in mice ...

Increased CD68 expression in the immunostaining data of DSS mice heart suggests the recruitment of inflammatory macrophages. At the molecular level, CDK9 expression was significantly increased in ...

To study the role of YOD1 in colitis, we generated Yod1−/− mice and found that ablation of YOD1 aggravated DSS-induced colitis. Deeper investigation of the functionality revealed that YOD1 ameliorated ...