Here, we investigated the function of intestinal epithelial toll-like receptor (TLR) responses in the dextran sodium sulfate (DSS)-induced mouse model of colitis ... For staining of macrophages and ...

Ulcerative colitis (UC) is a chronic inflammatory bowel disorder of ... The effects of berberrubine on UC were determined by the DSS-induced mouse model due to its anti-inflammatory and antibacterial ...

Monocyte-like macrophage (MLM) accumulation precedes colitis-associated tumour formation and contributes to inflammatory macrophage polarisation. Interruption of MLM recruitment into the colon reduces ...

Palisade Bio presented a poster titled “PALI-2108, a Colon-Specific PDE4B Inhibitor Prodrug, Reduces Ulcerative Colitis Symptoms in an Acute Colitis DSS Mouse Model” at the Crohn’s & Colitis Congress ...

Researchers from Ocean University of China and Qingdao Marine Science and Technology Center published data from a preclinical study that investigated the impact of the quinazolinone derivative MR-2938 ...

Collagenous colitis and lymphocytic colitis, the two main subtypes of microscopic colitis, may develop as a result of an immune response. This could happen when something causes the body to ...

Janus kinase (JAK) inhibitors can quickly and effectively manage ulcerative colitis (UC), especially when more conventional treatments haven’t worked. UC is a type of inflammatory bowel disease ...

Proctitis affects the rectum, whereas ulcerative colitis can affect the colon, the rectum, or both parts of the intestine. Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD ...

Intestinal fibrosis, as a late-stage complication of inflammatory bowel disease (IBD), leads to bowel obstruction and requires surgical intervention, significantly lowering the quality of life of ...

Conclusion: Therefore, B. acidifaciens and its derived EVs can alleviate DSS-induced colitis by reducing mucosal damage to colon tissue, reducing inflammatory response, promoting mucosal barrier ...