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The DNA copy that is made, called complementary DNA (cDNA), is then applied to the microarray. The cDNA binds to complementary base pairs in each of the spots on the array, a process known as ...
In a typical experiment, a microarray is prepared and mounted in a well chamber and the DNA is hybridized (a standard technique in which complementary single strands of DNA bind to form double ...
In a microarray experiment the glass slide with the labeled DNA of interest plays a key role. As can be seen, a solid surface (in this example a glass microscope slide) contains thousands of spots.
One-color experiments (panel b in the figure) are performed in a similar manner, except that the DNA is labeled with a single color and hybridized to a microarray without a reference sample.
Chips containing orderly arrays of thousands of DNA sequences--so-called DNA microarrays--have become an indispensable part of the biologist's tool kit for studying gene expression and gene ...
The new method, which blends experiment and computation, strengthens DNA microarray analysis, according to its Carnegie Mellon University inventor, who is publishing his findings in the December ...
A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in studies of multiple ...
In a typical experiment, a microarray is prepared and mounted in a well chamber and the DNA is hybridized (a standard technique in which complementary single strands of DNA bind to form double ...
Technology Insight: Tuning into the Genetic Orchestra Using Microarrays-Limitations of DNA Microarrays in Clinical Practice Ambreen Abdullah-Sayani; Jolien M. Bueno-de-Mesquita; Marc J. van de Vijver ...
The new method, which blends experiment and computation, strengthens DNA microarray analysis, according to its Carnegie Mellon University inventor, who is publishing his findings in the December ...