The activity of these "switches" is regulated by their methylation status, chemical marks that can be added to or removed ...

A recent review by Prof. Zhu Bing and Associate Professor Xiong Jun from the Institute of Biophysics of the Chinese Academy ...

Now, researchers from Kyushu University have demonstrated that the histone modification H3K4me3 in mature mouse oocytes is directly involved in chromosome and spindle stabilization and is crucial ...

Congenital heart disease (CHD) affects approximately 1% of live births. Thanks to surgical advancements, infants born with CHD are now surviving into adulthood. However, these individuals face a high ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in the January 2025 issue of Clinical Reviews in Allergy & Immunology by Pan ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age.

While each cell contains the complete genetic blueprint of an organism, chemical marks on the DNA – so-called epigenetic modifications – control which genes are active when and where. A team ...

Methylation of cytosine in CpG dinucleotides and histone lysine and arginine residues is a chromatin modification that critically contributes to the regulation of genome integrity, replication, and ...

A UCLA-led study has created a map of DNA modification in two regions of the brain critical to learning, memory and emotional regulation. The map offers a benchmark for ensuring stem cell-based ...

Epigenetics involves a series of biological processes that regulate chromatin-mediated DNA templates. 2 Cancer is a ...

Several reviews have highlighted the significance of DNA methylation and noncoding RNA in the development of hypertension. 16, 19–21 Our primary focus is on elucidating the roles of various enzymes ...