The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in the January 2025 issue of Allergy and Immunology by Pan et al. Epigenetic ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Previously defined epigenetic mechanisms, such as DNA methylation and histone modification, are also important modifiers of gene expression. In some species, regulatory RNAs possess epigenetic ...

which inhibits DNA methylation. Drugs aimed at histone modifications are called histone deacetylase (HDAC) inhibitors. HDACs are enzymes that remove the acetyl groups from DNA, which condenses ...

Why do beauty standards feel inescapable? Neuroscience and epigenetics reveal how our brains imprint cultural ideals—shaping ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

The way the body ages could be more resilient than previously thought, a new study suggests.

Histones consisting of H2A, H2B, H3, and H4 are proteins that are critical in the packing of DNA into the cell. Lysine residues in N-terminal tails of histone H3 are the major targets for ...

These modifications not only affect gene expression but also impact critical biological behaviors of tumor cells, including proliferation, differentiation, apoptosis, invasion, and metastasis. Notably ...

Epigenetic dysregulation has been strongly implicated in psychiatric disorders. Epigenetic modifications, such as DNA methylation and histone modifications, can be affected by both genetic and ...