LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage biopharmaceutical company developing innovative treatments that exploit specific cancer cell vulnerabilities while ...

Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication. Neurons, however, do not divide. For this reason, they are at ...

Get Instant Summarized Text (Gist) DNA damage in healthy cells can persist unrepaired for years, challenging traditional views on mutation formation. This persistence allows multiple opportunities ...

Sunburn has traditionally been attributed to UV-induced DNA damage. However, a new study by the University of Copenhagen and Nanyang Technological University, Singapore, reveals that RNA ...

Researchers at the Wellcome Sanger Institute have uncovered a surprising form of DNA damage that persists for years without repair, posing risks for generating harmful mutations. The findings shed ...

Separately, Rakovina Therapeutics expects to receive the first synthesized drug candidates from its second AI-driven drug ...

Many people follow the golden rules of avoiding direct sunlight between the hours of noon and 3 p.m., staying in […] ...

A recent Surgeon General's report highlighted alcohol's carcinogenic effects. A Penn State professor breaks down the process.

"Sunburn damages the DNA, leading to cell death and inflammation. So the textbooks say. But in this study we were surprised to learn that this is a result of damage to the RNA, not the DNA that ...