Accumulation of NEAT1 at DNA double-strand breaks (NGS data, top) and defects in DNA damage signaling in NEAT1-deficient cells (merged confocal imaging data, bottom). Credit: Mamontova et al. 2024 ...

Rosalind Franklin’s X-ray diffraction images were pivotal in revealing the helical structure of DNA, contributing significantly to Watson and Crick’s model.

And like natural language, DNA has a natural structure. The sequences are not random. A lot of structure in natural language is also informal; it can be ambiguous, and it’s changing all the time. In ...

How cells recognize and repair DNA damage Date: October 4, 2024 Source: University of Würzburg Summary: Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. Explore new technology used in the St. Jude-led discovery.

Researchers uncover human DNA repair by nuclear metamorphosis Date: April 17, 2024 Source: University of Toronto Summary: Researchers have discovered a DNA repair mechanism that advances ...

In this study, the DNA signal strand is expressed in the form of domain coding. As shown in Figure 1, the domain coding strand consists of four single strands, namely, A0, A1, A2, and A3. Each strand ...

The first human trials of DNA vaccines designed to produce live viruses in people’s bodies could start next year. A US company called Medigen has told New Scientist it is seeking approval for ...

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to ...

Mark Lorch does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...