Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target. ScienceDaily . Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 03 ...

Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target Peer-Reviewed Publication. Memorial Sloan Kettering Cancer Center ...

Cryo-electron microscopy makes biological molecules like proteins, DNA, ... Henderson's 1990 cryo-electron microscopy image of bacteriorhodopsin was far more detailed.

Scientists are reporting the first 3-D images of an individual protein ever obtained with enough clarity to determine its structure. When Gang Ren whirls the controls of his cryo-electron ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights ...

When Gang Ren whirls the controls of his cryo-electron microscope, he compares it to fine-tuning the gearshift and brakes of a racing bicycle. But this machine at the U.S. Department of Energy ...

Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and viruses, at near-atomic resolution.

Proteins from 40 kDa to several MDa in size can be studied by this methodology. Very little sample is required for this technique. For cryo-EM the specimen, typically a purified protein sample, is ...

Cryo-electron microscopy adds the element of super-cold temperatures, making it particularly useful for near-atomic structure resolution of larger proteins, membrane proteins or lipid-containing ...

Dahlberg combines the imaging techniques of cryogenic electron tomography and super-resolution fluorescence microscopy to obtain high-resolution images of things like this bacterial cell.

The Andhra phage Image credit: Dokland lab Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail. This is ...

For example, regions of the genome that are rich in guanine bases (represented by G in the DNA code) can fold into a DNA structure called a G-quadruplex, or G4 for short, which is more compact than ...