The “classical” pathway of the complement system is triggered when C1q binds to antibodies that are already bound to antigens on a cell surface.

Konwar S, Schroda S, Rogg M, et al. Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis. J Clin Invest.Published online ...

The chief executive officer of NatView Technology, Nurudeen Maidoki, said the newly launched National Volunteer Database will enhance volunteer efforts ...

The complement system is a key component of innate and adaptive immunity and therefore acts as a vital defense against invading pathogens. Deficiencies in the complement system are associated with ...

Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer—activation of the complement system. A new article in ...

Researchers have identified a blood protein ‘signature’ in the complement system, part of the immune system, of patients with long COVID that may improve the diagnosis and lead to a treatment ...

When the results pointed to abnormal activation of the complement system as a distinguishing feature of long covid, “we all of a sudden said ‘Oh, this makes so much sense,’” Boyman says.

Complement system causes cell damage in long Covid Date: January 18, 2024 Source: University of Zurich Summary: Long Covid patients suffer from chronic symptoms such as fatigue or shortness of breath.

image: “In patients with Long Covid, the complement system no longer returns to its basal state.” Onur Boyman, professor of immunology at University of Zurich ...

The limbic system helps regulate emotional and social processing, as well as learning, motivation, and memory. It consists of structures that lie beneath the outer, wrinkly part of the brain and ...

Immunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. While much focus has been on engaging T-cells for fighting cancer, less attention has been ...