Age-related macular degeneration (AMD) remains a leading cause of vision loss, but new therapies are reshaping its treatment.

Our data indicate that blocking the complement system exacerbates LCWE-induced KD vasculitis, potentially by impairing C3-mediated clearance of bacterial components. Our studies reveal the ...

The fourth fundamental circuit component that is frequently employed to design nanoscale electronic devices is memristor. The compact size, non-volatility, and low power of memristor, combined with ...

As the hydrogen flows through the system, it first cools high-efficiency components operating at cryogenic temperatures, such as high-temperature superconducting generators and cables.

Inflammatory proteins (cytokines or chemokines), cells (neutrophils, T-cells, and dendritic cells), complement system components, and pathogenic antibodies are present on the ocular surface in ...

These included protein networks related to Type I and II interferons and NOD-like receptor signaling, increased complement system components, immunoproteasome, and previously suggested predictive ...

ARO-C3: Arrowhead Pharmaceuticals ARO-C3 is an investigational RNA interference (RNAi) therapy designed to target and inhibit the production of complement C3, a key component of the immune system ...

The complement system, specifically the alternative pathway (AP), plays an important role in the development of AMD, and increasing local FI concentration could be a promising approach to regulate ...

The C-terminal fragment functions as a cysteine protease with a unique proteolytic activity and structure, which degrades several components of the complement system, such as C3 and C3b. Murine ...

It is now apparent that immune mediators including complement, cytokines, and cells of the innate and adaptive immune system contribute not only to blood pressure elevation but also to the target ...