The FDA has increasingly issued guidelines and set expectations for industry to enroll clinically relevant and diverse trial populations. 1 Prior to the enactment of legislation through the Food and ...

Background: Anti-VEGF antibodies combined with chemotherapy remain first-line treatment for unresectable metastatic colorectal cancer (mCRC), but no randomised trials have evaluated oral VEGFR-TKI ...

Introduction Patients with node-positive breast cancer having primary surgery currently undergo axillary node clearance (ANC) to reduce the risk of breast cancer recurrence. Evidence that this highly ...

Post-hoc analyses of a large, randomized clinical trial have revealed the potential advantages associated with electronic informed consent (eConsent) in acute ischemic stroke studies, including ...

Background: Clinical trial designs have historically been biased towards the Caucasian population, with limited representation of minorities due to factors such as financial barriers, inequity, and ...