The study explores molecular mechanisms underlying synaptic plasticity - the strengthening or weakening of neuronal connections that enable learning and memory.

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage.

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

enabling researchers to see the inner workings of cells in fine detail. Collectively called volume electron microscopy, or volume EM, these methods use electron microscopes to image thin layers of ...

In biology textbooks, the endoplasmic reticulum is often portrayed as a distinct, compact organelle near the nucleus, and is commonly known to be ...

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances.

The new research reveals a novel mechanism for signal transmission in brain cells and helps answer an open question in neuroscience about how intracellular signals travel over long distances in ...